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pentobarbital will lessen the extent or impact of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with sturdy CYP3A4 inducers just isn't recommendedpentobarbital will minimize the extent or influence of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will less